Pitx genes regulate expression of Shroom3, a gene controlling cell shape change
نویسندگان
چکیده
منابع مشابه
Direct activation of Shroom3 transcription by Pitx proteins drives epithelial morphogenesis in the developing gut.
Individual cell shape changes are essential for epithelial morphogenesis. A transcriptional network for epithelial cell shape change is emerging in Drosophila, but this area remains largely unexplored in vertebrates. The distinction is important as so far, key downstream effectors of cell shape change in Drosophila appear not to be conserved. Rather, Shroom3 has emerged as a central effector of...
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ژورنال
عنوان ژورنال: Developmental Biology
سال: 2009
ISSN: 0012-1606
DOI: 10.1016/j.ydbio.2009.05.183